This guidance note provides ten core principles that practitioners can follow when aiming to integrate livelihoods and protection programming in urban humanitarian response, with a focus on supporting economic outcomes for beneficiaries. Key actions in programme design, illustrative performance indicators, notes on sustainability, and brief case examples are included. While the note is derived from experiences serving Syrian refugees in Lebanon and Jordan, its principles were chosen from a global desk review of relief efforts in urban humanitarian settings to provide informed guidance that has universal applicability.